Doctoral student in chemistry

2019-10-03

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Job description

A four-year Ph.D. Research Fellowship is available at the Host Response to Biomaterials Laboratory at the Linnaeus University, Centre for Biomaterials Chemistry, Sweden. The subject of our research is to study how biomaterials perform in a biological system, with focus on the intravascular instant immune activation and thrombotic response (i.e., thromboinflammation). The main goal is to advance the understanding of the mechanisms behind adverse reactions to biomaterials in clinical use, to make treatment with biomaterials better and safer.

This Ph.D. project combines research in innate immunity and hemostasis with biomaterials science. The project will include the development of experimental whole blood models, and evaluation of inflammatory and thrombotic responses in human whole blood after biomaterial contact. The primary focus is thromboinflammatory complications in response to treatment with a mechanical heart pump (i.e., ventricular assist device) and challenges in nanoparticle drug delivery systems. Methodologies that will be relevant are human whole blood- and possibly animal-models, techniques for cell culturing and analysis (flow cytometry, microscopy, etc.), biomarker analysis (ELISA, western blot) and may also include methods for biomaterial modification.

The research will be performed at Linnaeus University, Centre for Biomaterials Chemistry, Kalmar, Sweden, in close collaboration with the University of Oslo and Oslo University Hospital, Norway. There will be the opportunity to perform parts of the project in Oslo. The candidate will join a strong and interactive research environment.

According to the Higher Education Ordinance, a person appointed to a doctoral studentship should primarily devote himself/herself to his/her own studies. An appointee may, however, work to a limited extent with education, research, artistic development, and administration. However, before a doctoral degree has been awarded, duties of this kind may not comprise more than 20% of a full-time post.

Requirements

Applicants fulfill the general entry requirements if they

• Have been awarded a degree on second-cycle level

• Have satisfied the requirements for courses comprising at least 240 credits, of which 60 credits on second-cycle level, or in another way, in Sweden or abroad, have acquired principally equivalent knowledge. 

Assessment grounds

• A degree in biology or medicine, and knowledge in immunology and/or biomaterial chemistry are beneficial.

• Experience of cell culture techniques, animal experiments, and other relevant molecular and cellular techniques is advantageous.

• Importance will be attached to the compatibility of the applicant’s professional and personal disposition. We aim to find a candidate who is highly motivated for research studies, ambitious, collaborative, independent and structured.

• Importance will also be attached to the applicant’s proficiency in written and oral English.

Evaluation and selection criteria

The selection of candidates is made with regard to the applicants’ ability to successfully complete and benefit from their studies at the graduate level. More information about the evaluation and selection criteria can be found in the subject area’s general syllabus, see https://lnu.se/en/education/PhD-studies/.

Employment

The employment as a doctoral student is limited according to chapter 5, § 7 of the Higher Education Ordinance. The total employment period may not be longer than the equivalent full-time postgraduate studies of four years.

You will find more useful information about the position at: https://lnu.se/mot-linneuniversitetet/Lediga-jobb/?rmpage=job&rmjob=4665&rmlang=SE

We need your application no later than the 4th of November. Apply by clicking on the "Apply" button at the bottom of the ad or by following the link to the full ad on our homepage. All documents cited must be received by the University no later than 24.00 (Local time in Sweden) on the closing day.

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